Hydroxyzine See: H996500
Hydroxyzine See: H996500
CAS: 68-88-2
Molecular Formula: C21H27ClN2O2
Hydroxyzine See: H996500 - Names and Identifiers
Hydroxyzine See: H996500 - Physico-chemical Properties
| Molecular Formula | C21H27ClN2O2 |
| Molar Mass | 374.9 |
| Density | 1.1020 (rough estimate) |
| Melting Point | 190°C |
| Boling Point | 250 °C(Press: 0.1 Torr) |
| Water Solubility | < 700 mg/mL |
| Solubility | Chloroform (Slightly), DMSO (Sparingly), Ethanol (Slightly), Methanol (Slightly, |
| Appearance | Oil to Gel |
| Color | Colourless to Yellow Thick |
| pKa | pKa 1.96± 0.05；7.40± 0.03(H2O,t =24.5±0.5)(Approximate) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.5400 (estimate) |
| In vitro study | Hydroxyzine dihydrochloride inhibits carbachol (10 μM)-induced serotonin release by 34% at 10 μM, by 25% 1 μM and by 17% 0.1 μM in pretreated bladder slices for 60 min. |
| In vivo study | Hydroxyzine dihydrochloride (12.5 mg/kg, 25 mg/kg and 50 mg/kg i.p.) shows little direct analgesic activity but markedly potentiates only the effect of morphine on the vocalization after-discharge which represents the affective component of pain in rats. Hydroxyzine dihydrochloride (50 mg/kg i.p.) potentiates morphine on the tail-flick test, while Hydroxyzine (12.5 mg/kg i.p.) decreases morphine antinociception in rats. |
Hydroxyzine See: H996500 - Risk and Safety
| Toxicity | LD50 oral in rat: 840mg/kg |
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Spot supply
Product Name: Hydroxyzine Monomer Visit Supplier Webpage Request for quotationCAS: 68-88-2
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Hydroxyzine See: H996500 Visit Supplier Webpage Request for quotationCAS: 68-88-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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